eGFR
The estimated glomerular filtration rate assesses the filtration function of the kidneys and is calculated from some basic laboratory and demographic data.
d. Schwartz's formula
Assessment of eGFR in children
eGFR [ml / min / 1.73 m2] = 0.413 x body height [cm] / Screat [mg/dl]
Interpretation:
≥ 90 normal to increased GFR
60-89 slight reduction in GFR
45-59 slight to moderate reduction in GFR
30-44 moderate to severe reduction in GFR
15-29 severe reduction in GFR
<15 end-stage renal disease
Standard Kt/V (stdKt/V)
Equation for Estimation of Standard Kt/V (stdKt/V)
Single-pool Kt/V
Equation I
spKt / V = − ln ( C 1 / C 0 − 0,008 ∗ t ) + ( 4 − 3,5 ∗ C 1 / C 0 ) ∗ UF/ WspKt/V=-ja(do1/do0-0,008*t)+(4-3,5*do1/do0)*UF/W
where C0 is pre-dialysis BUN (in milligrams per decilitre),
C1 is the post-dialysis BUN (in milligrams per decilitre),
t is session length in hours,
UF is the ultrafiltrate in kilograms
W is post-dialysis weight in kilograms.
TSAT
Iron transferrin saturation (TSAT) – iron availability for current erythropoiesis
TSAT = Serum Fe concentration × 100/Total Fe binding capacity (TIBC)
Iron deficiency TSAT <20%
Target value> 30%
BMI
The body mass index (BMI) is calculated by dividing body weight (kg) by the square of body height (m). The classification (value range) for BMI has been developed for adults only and must not be used for children.
| BMI(kg/m2) | Body weight | Category | The risk of obesity accompanying diseases |
|---|---|---|---|
| < 16,0 | underweight | starvation | At minimum but increased levels of other health problems |
| 16,0-16,99 | emaciation | ||
| 17,0-18,49 | underweight | ||
| 18,5-24,99 | optimum | desired body weight | minimal |
| 25,00-29,99 | overweight | overweight | average |
| 30,00-34,99 | obesity | 1st degree obesity | high |
| 35,0-39,99 | 2nd degree obesity (high) | very high | |
| ≥ 40,0 | 3rd degree obesity (pathological) | extreme level of risk |
HOMA index
The basic test in the diagnosis of insulin resistance is the determination of fasting glucose and insulin levels in the blood serum. Based on these values, the so-called HOMA-IR indicator (Homeostatic Model Assessment – Insulin Resistance) is calculated. It is calculated on the basis of the following formula:
HOMA-IR = fasting insulin mU/ml × fasting glucose (mmol/l)/22.5.
Interpretation of the result:
2,5 - normal
2.5 – 4.0 suspected insulin resistance
Modified Early Warning Score
MEWS – Modified Early Warning Scoring. It is used to identify patients at risk of deterioration of the general condition that may be a threat to patients health or life. It is an element of the assessment of risk of ICU hospitalisation and death.
Interpretation:
0-2 – routine care
3 – the need for increased watchfulness in care, assessment of the condition every 2 hours,
4 – constant monitoring of vital signs, including a pulseoximeter
> or = 5 – call an anaesthesiologist to assess indications for transfer to ICU